autologous anti-PD-1 antibody-activated tumor-infiltrating lymphocytes

{
  "id": "MLC-T-ONC-011489",
  "term": "autologous anti-PD-1 antibody-activated tumor-infiltrating lymphocytes",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous tumor infiltrating lymphocytes (TILs) activated by an anti-programmed cell death protein 1 (PD1) antibody, with potential immunomodulating activity. The autologous TILs are isolated from an autologous tumor sample and ex-vivo activated in the presence of anti-PD-1 antibody. Upon infusion of the autologous anti-PD1 antibody-activated TILs back into the patient, the cells specifically target and kill the patient's tumor cells.",
  "synonyms": [
    "autologous anti-PD-1 antibody-activated TILs",
    "anti-PD1 antibody-activated autologous TILs"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-anti-pd-1-antibody-activated-tumor-infiltrating-lymphocytes/"
}