autologous HPV16/HPV18/Survivin-specific CD8+ T cells NEXI-003

{
  "id": "MLC-T-ONC-011652",
  "term": "autologous HPV16/HPV18/Survivin-specific CD8+ T cells NEXI-003",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous CD3+ CD4- CD8+ T cells targeting multiple human papilloma virus (HPV) tumor-associated antigens, including HPV types 16 and 18 antigens and survivin, with potential immunomodulating and antineoplastic activities. Following leukapheresis and ex vivo priming and expansion, the autologous HPV16/HPV18/survivin-specific CD8+ T cells NEXI-003 are re-introduced into the patient, where they target and kill tumor cells expressing these HPV tumor-associated antigens.",
  "synonyms": [
    "autologous HPV tumor-relevant antigen-specific CD8+ T cells NEXI-003",
    "CD3+ CD4- CD8+ T cells NEXI-003"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-hpv16-hpv18-survivin-specific-cd8-plus-t-cells-nexi-003/"
}