autologous multiple antigen-specific T cells MASE-T

{
  "id": "MLC-T-ONC-011708",
  "term": "autologous multiple antigen-specific T cells MASE-T",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous T cells targeting multiple antigens expressed by melanoma cells, with potential immunomodulating and antineoplastic activities. Peripheral blood T cells from the patient are collected, processed with artificial antigen-presenting scaffolds, and enriched and expanded ex-vivo to generate multiple antigen-specific endogenously-derived T cells (MASE-T) targeting multiple antigens expressed by melanoma cells. Upon administration, the autologous multiple antigen-specific T cells MASE-T are re-introduced into the patient, where they target and kill melanoma cells expressing these specific antigens.",
  "synonyms": [
    "MASE-T cells",
    "multiple antigen-specific endogenously-derived T cells",
    "multiple antigen specific endogenously derived T cells",
    "MASE-T"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-multiple-antigen-specific-t-cells-mase-t/"
}