MLchartDataset catalogue

BMS-184476

Term · Oncology and biomedicine · MLC-T-ONC-001143

  1. A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called mitotic inhibitors.

  2. A 7-methylthiomethyl ether derivative of paclitaxel with antineoplastic activity. BMS-184476 binds to and stabilizes the resulting microtubules, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and apoptosis. (NCI)

Table 1. Record
IdentifierMLC-T-ONC-001143
FieldOncology and biomedicine
ReferencesNCI Dictionary of Cancer Terms; National Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-001143",
  "term": "BMS-184476",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called mitotic inhibitors.",
    "A 7-methylthiomethyl ether derivative of paclitaxel with antineoplastic activity. BMS-184476 binds to and stabilizes the resulting microtubules, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and apoptosis. (NCI)"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/bms-184476/"
}

Record 3,694 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.