MLchartDataset catalogue

TPI 287

Term · Oncology and biomedicine · MLC-T-ONC-017283

A synthetic, third generation taxane with potential antineoplastic activity. TPI 287 binds to tubulin and stabilizes microtubules, resulting in inhibition of microtubule assembly/disassembly dynamics, cell cycle arrest at the G2/M phase, and apoptosis.

Table 1. Record
IdentifierMLC-T-ONC-017283
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-017283",
  "term": "TPI 287",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic, third generation taxane with potential antineoplastic activity. TPI 287 binds to tubulin and stabilizes microtubules, resulting in inhibition of microtubule assembly/disassembly dynamics, cell cycle arrest at the G2/M phase, and apoptosis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/tpi-287/"
}

Record 16,570 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.