Corticosteroid-containing eye drop

{
  "id": "MLC-T-ONC-012780",
  "term": "Corticosteroid-containing eye drop",
  "field": "Oncology and biomedicine",
  "definition": "A sterile ophthalmic solution containing a corticosteroid, with anti-inflammatory activity. Upon application of the corticosteroid-containing eye drop into the eye, the corticosteroid binds to cytoplasmic receptors, translocates to the nucleus and subsequently initiates the transcription of glucocorticoid-responsive genes such as lipocortins to inhibit phospholipase A2. This prevents the release of arachidonic acid, a precursor to prostaglandins and leukotrienes, both important mediators in the pro-inflammatory response mechanism.",
  "synonyms": [
    "corticosteroid eye drop",
    "corticosteroid ophthalmic solution",
    "steroidal eye drops"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/corticosteroid-containing-eye-drop/"
}