foslevcromakalim
Term · Oncology and biomedicine · MLC-T-ONC-013765
An ophthalmic solution containing a prodrug of levcromakalim, a modulator of the adenosine triphosphate (ATP)-sensitive potassium (KATP) channel, with potential vasodilating and episcleral venous pressure (EVP)-lowering activities. Upon application into the eye, foslevcromakalim is converted to levcromakalim, which dilates blood vessels by opening the KATP channel. This lowers both EVP and elevated intraocular pressure (IOP).
| Identifier | MLC-T-ONC-013765 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | levcromakalim prodrug eye drop QLS-101; levcromakalim prodrug QLS-101; levcromakalim phosphate; levcromakalim prodrug ophthalmic solution QLS-101 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013765",
"term": "foslevcromakalim",
"field": "Oncology and biomedicine",
"definition": "An ophthalmic solution containing a prodrug of levcromakalim, a modulator of the adenosine triphosphate (ATP)-sensitive potassium (KATP) channel, with potential vasodilating and episcleral venous pressure (EVP)-lowering activities. Upon application into the eye, foslevcromakalim is converted to levcromakalim, which dilates blood vessels by opening the KATP channel. This lowers both EVP and elevated intraocular pressure (IOP).",
"synonyms": [
"levcromakalim prodrug eye drop QLS-101",
"levcromakalim prodrug QLS-101",
"levcromakalim phosphate",
"levcromakalim prodrug ophthalmic solution QLS-101"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/foslevcromakalim/"
}
Record 7,585 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.