Cultured Lentinula edodes mycelia extract
Term · Oncology and biomedicine · MLC-T-ONC-012828
An orally bioavailable capsule-based formulation of a standardized extract of cultured Lentinula edodes (Shiitake mushroom) mycelia (ECLM), which is high in the polysaccharides beta- and alpha-glucans, with potential antioxidant, immunomodulating and antineoplastic activities. Upon oral administration, the cultured Lentinula edodes mycelia extract activates the immune system, by binding to toll-like receptors (TLRs), specifically TLR-4, and induces the activation of dendritic cells (DCs), natural killer (NK) cells, macrophages and T cells and the release of cytokines. This may clear human papillomavirus (HPV) infections.
| Identifier | MLC-T-ONC-012828 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | ECLM |
| Synonyms | L. edodes mycelia extract AHCC; Yinuojin Ruanjiaonang; standardized extract of cultured Lentinula edodes mycelia; Lentinula edodes mycelia extract; cultured Lentinula edodes mycelia extract AHCC |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-012828",
"term": "Cultured Lentinula edodes mycelia extract",
"field": "Oncology and biomedicine",
"definition": "An orally bioavailable capsule-based formulation of a standardized extract of cultured Lentinula edodes (Shiitake mushroom) mycelia (ECLM), which is high in the polysaccharides beta- and alpha-glucans, with potential antioxidant, immunomodulating and antineoplastic activities. Upon oral administration, the cultured Lentinula edodes mycelia extract activates the immune system, by binding to toll-like receptors (TLRs), specifically TLR-4, and induces the activation of dendritic cells (DCs), natural killer (NK) cells, macrophages and T cells and the release of cytokines. This may clear human papillomavirus (HPV) infections.",
"abbreviation": "ECLM",
"synonyms": [
"L. edodes mycelia extract AHCC",
"Yinuojin Ruanjiaonang",
"standardized extract of cultured Lentinula edodes mycelia",
"Lentinula edodes mycelia extract",
"cultured Lentinula edodes mycelia extract AHCC"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/cultured-lentinula-edodes-mycelia-extract/"
}
Record 5,498 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.