MLchartDataset catalogue

ECT-001 expanded cord blood

Term · Oncology and biomedicine · MLC-T-ONC-013205

A preparation of umbilical cord blood (UCB) co-cultured and expanded in an optimized culture system with a small molecule agonist of hematopoietic stem cell (HSC) renewal, with potential use in hematopoietic cell transplantation (HCT). Upon administration, the ECT-001 expanded cord blood cells increase and restore the number of hematopoietic stem and progenitor cells (HSPCs) that can differentiate into a variety of cell types and promote blood cell recovery. Compared to untreated UBCs, ECT-001 expanded UCB cells may exhibit enhanced stem cell proliferation and engraftment.

Table 1. Record
IdentifierMLC-T-ONC-013205
FieldOncology and biomedicine
SynonymsUM171 expanded cord blood; ECT-001 expanded umbilical cord blood; ECT-001 expanded UCB
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013205",
  "term": "ECT-001 expanded cord blood",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of umbilical cord blood (UCB) co-cultured and expanded in an optimized culture system with a small molecule agonist of hematopoietic stem cell (HSC) renewal, with potential use in hematopoietic cell transplantation (HCT). Upon administration, the ECT-001 expanded cord blood cells increase and restore the number of hematopoietic stem and progenitor cells (HSPCs) that can differentiate into a variety of cell types and promote blood cell recovery. Compared to untreated UBCs, ECT-001 expanded UCB cells may exhibit enhanced stem cell proliferation and engraftment.",
  "synonyms": [
    "UM171 expanded cord blood",
    "ECT-001 expanded umbilical cord blood",
    "ECT-001 expanded UCB"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ect-001-expanded-cord-blood/"
}

Record 6,362 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.