ECT-001 expanded cord blood
Term · Oncology and biomedicine · MLC-T-ONC-013205
A preparation of umbilical cord blood (UCB) co-cultured and expanded in an optimized culture system with a small molecule agonist of hematopoietic stem cell (HSC) renewal, with potential use in hematopoietic cell transplantation (HCT). Upon administration, the ECT-001 expanded cord blood cells increase and restore the number of hematopoietic stem and progenitor cells (HSPCs) that can differentiate into a variety of cell types and promote blood cell recovery. Compared to untreated UBCs, ECT-001 expanded UCB cells may exhibit enhanced stem cell proliferation and engraftment.
| Identifier | MLC-T-ONC-013205 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | UM171 expanded cord blood; ECT-001 expanded umbilical cord blood; ECT-001 expanded UCB |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013205",
"term": "ECT-001 expanded cord blood",
"field": "Oncology and biomedicine",
"definition": "A preparation of umbilical cord blood (UCB) co-cultured and expanded in an optimized culture system with a small molecule agonist of hematopoietic stem cell (HSC) renewal, with potential use in hematopoietic cell transplantation (HCT). Upon administration, the ECT-001 expanded cord blood cells increase and restore the number of hematopoietic stem and progenitor cells (HSPCs) that can differentiate into a variety of cell types and promote blood cell recovery. Compared to untreated UBCs, ECT-001 expanded UCB cells may exhibit enhanced stem cell proliferation and engraftment.",
"synonyms": [
"UM171 expanded cord blood",
"ECT-001 expanded umbilical cord blood",
"ECT-001 expanded UCB"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/ect-001-expanded-cord-blood/"
}
Record 6,362 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.