ex vivo-expanded HER2-specific T cells

{
  "id": "MLC-T-ONC-013482",
  "term": "ex vivo-expanded HER2-specific T cells",
  "field": "Oncology and biomedicine",
  "definition": "T cells specific for the human epidermal growth factor receptor 2 (HER2) with potential immunopotentiating activity. T cells directed against HER2, overexpressed on many tumor cells, are collected from HER2-expressing tumor tissue, expanded ex vivo and, then re-introduced in the patient. Re-introduction of ex vivo-expanded HER2-specific T cells may enhance the cytotoxic T cell response against tumor cells overexpressing HER2, resulting in inhibition of tumor growth.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ex-vivo-expanded-her2-specific-t-cells/"
}