fluorescent protease-activated peptide AVB-620

{
  "id": "MLC-T-ONC-013655",
  "term": "fluorescent protease-activated peptide AVB-620",
  "field": "Oncology and biomedicine",
  "definition": "A protease-cleavable peptide linked to a fluorescent probe, with potential imaging activity. Upon intravenous infusion of the fluorescent protease-activated peptide AVB-620 before surgery, the peptide moiety of AVB-620 can be cleaved by proteases overexpressed by tumor cells. This activates the fluorescent probe and the tumor cells expressing the proteases can be detected using a fluorescence imaging system. This allows for the visualization and removal of the tumor during surgery.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluorescent-protease-activated-peptide-avb-620/"
}