MLchartDataset catalogue

PSMA-targeting fluorescent imaging agent IS-002

Term · Oncology and biomedicine · MLC-T-ONC-016286

A near-infrared (NIR) fluorescent imaging agent targeting the tumor-associated antigen (TAA) prostate-specific membrane antigen (PSMA), that can potentially be used as a tumor-selective fluorescent imaging agent during NIR fluorescence imaging-guided surgery. Upon intravenous administration, the PSMA-targeting fluorescent imaging agent IS-002 targets and binds to PSMA on PSMA-expressing tumor cells. Upon fluorescent imaging, PSMA-expressing tumors can be visualized and identified, and surgically removed. PSMA is overexpressed by most prostate cancers.

Table 1. Record
IdentifierMLC-T-ONC-016286
FieldOncology and biomedicine
Synonymsfluorophore IS-002; PSMA-targeted fluorescent imaging agent IS-002
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-016286",
  "term": "PSMA-targeting fluorescent imaging agent IS-002",
  "field": "Oncology and biomedicine",
  "definition": "A near-infrared (NIR) fluorescent imaging agent targeting the tumor-associated antigen (TAA) prostate-specific membrane antigen (PSMA), that can potentially be used as a tumor-selective fluorescent imaging agent during NIR fluorescence imaging-guided surgery. Upon intravenous administration, the PSMA-targeting fluorescent imaging agent IS-002 targets and binds to PSMA on PSMA-expressing tumor cells. Upon fluorescent imaging, PSMA-expressing tumors can be visualized and identified, and surgically removed. PSMA is overexpressed by most prostate cancers.",
  "synonyms": [
    "fluorophore IS-002",
    "PSMA-targeted fluorescent imaging agent IS-002"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/psma-targeting-fluorescent-imaging-agent-is-002/"
}

Record 13,820 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.