FOLFIRI regimen

{
  "id": "MLC-T-ONC-003286",
  "term": "FOLFIRI regimen",
  "field": "Oncology and biomedicine",
  "definitions": [
    "An abbreviation for a chemotherapy combination used to treat advanced colorectal cancer that has spread. It is also being studied in the treatment of other types of cancer. It includes the drugs leucovorin calcium (folinic acid), fluorouracil, and irinotecan hydrochloride. Also called FOLFIRI.",
    "A regimen consisting of leucovorin calcium (calcium folinate), 5-fluorouracil, and irinotecan that can be used in the treatment of appendiceal, small bowel, pancreatic and occult primary adenocarcinoma; colorectal, esophageal and esophagogastric junction, gastric, and hepatobiliary cancers; well-differentiated grade 3 neuroendocrine tumors (NETs), and extrapulmonary poorly differentiated neuroendocrine carcinoma, large or small cell carcinoma and mixed neuroendocrine-non-neuroendocrine neoplasm."
  ],
  "abbreviation": "FOLFIRI",
  "synonyms": [
    "FOLFIRI",
    "FOLinic acid-fluorouracil-IRInotecan regimen",
    "fluorouracil-folinic acid-irinotecan",
    "fluorouracil/folinic acid/irinotecan",
    "fluorouracil/leucovorin/irinotecan",
    "folinic acid/fluorouracil/irinotecan regimen"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/folfiri-regimen/"
}