FOLFIRINOX regimen

{
  "id": "MLC-T-ONC-003293",
  "term": "FOLFIRINOX regimen",
  "field": "Oncology and biomedicine",
  "definitions": [
    "An abbreviation for a chemotherapy combination used to treat pancreatic cancer that has spread to other parts of the body. It includes the drugs leucovorin calcium (folinic acid), fluorouracil, irinotecan hydrochloride, and oxaliplatin. Also called FOLFIRINOX.",
    "A regimen consisting of fluorouracil, irinotecan, leucovorin and oxaliplatin that can be used for the treatment of pancreatic and colorectal cancers; occult primary, appendiceal and small bowel adenocarcinomas; well-differentiated grade 3 neuroendocrine tumors (NETs), and extrapulmonary poorly differentiated neuroendocrine carcinoma, large or small cell carcinoma and mixed neuroendocrine-non-neuroendocrine neoplasm."
  ],
  "synonyms": [
    "FOLFIRINOX",
    "fluorouracil-leucovorin-irinotecan-oxaliplatin regimen",
    "fluorouracil with irinotecan hydrochloride, leucovorin calcium and oxaliplatin",
    "FOLFIRINOX protocol",
    "fluorouracil/irinotecan/leucovorin calcium/oxaliplatin",
    "folinic acid/fluorouracil/irinotecan/oxaliplatin"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/folfirinox-regimen/"
}