Founder mutation

{
  "id": "MLC-T-ONC-003334",
  "term": "Founder mutation",
  "field": "Oncology and biomedicine",
  "definition": "A genetic alteration observed with high frequency in a group that is or was geographically or culturally isolated, in which one or more of the ancestors was a carrier of the altered gene. This phenomenon is often called a founder effect. Also called founder variant.",
  "synonyms": [
    "founder variant"
  ],
  "references": [
    "NCI Dictionary of Genetics Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/founder-mutation/"
}