MLchartDataset catalogue

Founder variant

Term · Oncology and biomedicine · MLC-T-ONC-003335

A genetic alteration observed with high frequency in a group that is or was geographically or culturally isolated, in which one or more of the ancestors was a carrier of the altered gene. This phenomenon is often called a founder effect. Also called founder mutation.

Table 1. Record
IdentifierMLC-T-ONC-003335
FieldOncology and biomedicine
Synonymsfounder mutation
ReferencesNCI Dictionary of Genetics Terms
Record as JSON 
{
  "id": "MLC-T-ONC-003335",
  "term": "Founder variant",
  "field": "Oncology and biomedicine",
  "definition": "A genetic alteration observed with high frequency in a group that is or was geographically or culturally isolated, in which one or more of the ancestors was a carrier of the altered gene. This phenomenon is often called a founder effect. Also called founder mutation.",
  "synonyms": [
    "founder mutation"
  ],
  "references": [
    "NCI Dictionary of Genetics Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/founder-variant/"
}

Record 7,595 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.