Imiquimod

{
  "id": "MLC-T-ONC-004189",
  "term": "Imiquimod",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used to treat certain skin conditions. Imiquimod is used under the brand names Aldara and Zyclara to treat actinic keratosis (a skin condition that may become cancer) in adults who have a normal immune system and to treat genital warts or perianal warts in adults and in children aged 12 years or older. The Aldara brand of imiquimod is also used to treat superficial basal cell skin cancer in adults who have a normal immune system. Imiquimod is also being studied in the treatment of other conditions and types of cancer. It may help the immune system kill abnormal cells, including cancer cells. Imiquimod is a type of immunomodulating agent.",
    "A synthetic agent with immune response modifying activity. As an immune response modifier (IRM), imiquimod stimulates cytokine production, especially interferon production, and exhibits antitumor activity, particularly against cutaneous cancers. Imiquimod's proapoptotic activity appears to be related to Bcl-2 overexpression in susceptible tumor cells."
  ],
  "abbreviation": "IMQ",
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/imiquimod/"
}