iobenguane I 131

{
  "id": "MLC-T-ONC-004487",
  "term": "iobenguane I 131",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug that contains a form of radioactive iodine and is used to treat adults and children aged 12 years and older with certain types of malignant pheochromocytoma or paraganglioma that have spread or cannot be removed by surgery. It is also being studied in the treatment of other types of cancer. Iobenguane I 131 builds up in tumor cells and gives off radiation that may kill them. It is a type of radiotherapeutic agent. Also called 131I-MIBG, Azedra, and iodine I 131-metaiodobenzylguanidine.",
    "An I 131 radioiodinated synthetic analogue of the neurotransmitter norepinephrine. Iobenguane localizes to adrenergic tissue and, in radioiodinated forms, may be used to image or eradicate tumor cells that take up and metabolize norepinephrine."
  ],
  "synonyms": [
    "131I-MIBG",
    "Azedra",
    "iodine I 131-metaiodobenzylguanidine",
    "AdreView",
    "(131)I-MIBG",
    "I 131 metaiodobenzylguanidine",
    "I-131 meta-iodobenzylguanidine",
    "MIBG I-131",
    "iodine I 131 metaiodobenzylguanidine",
    "I 131 Meta-iodobenzylguanidine",
    "I-131 Metaiodobenzylguanidine",
    "Iobenguane (131I)"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iobenguane-i-131/"
}