cold contaminant-free Iobenguane I-131

{
  "id": "MLC-T-ONC-012698",
  "term": "cold contaminant-free Iobenguane I-131",
  "field": "Oncology and biomedicine",
  "definition": "An I 131 radioiodinated synthetic analogue of the neurotransmitter norepinephrine, manufactured with a proprietary process, with radioisotopic and potential antineoplastic activities. Cold contaminant-free iobenguane I 131 (MIBG) localizes to adrenergic tissue and may be used to image or eradicate tumor cells that accumulate and metabolize norepinephrine. This agent is manufactured using a technology that avoids the production of unwanted \"cold contaminants\" (i.e., carrier molecules), which may cause undesirable side effects and compete with MIBG for binding on target receptor sites.",
  "abbreviation": "Ultratrace MIBG",
  "synonyms": [
    "cold contaminant-free I 131-MIBG",
    "ultratrace iodine I 131 metaiodobenzylguanidine",
    "cold contaminant-free iodine I 131 metaiodobenzylguanidine",
    "cold contaminant-free iobenguane I 131"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/cold-contaminant-free-iobenguane-i-131/"
}