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iodine-123 metaiodobenzylguanidine

Term · Oncology and biomedicine · MLC-T-ONC-014543

The neurotransmitter analogue 3-nitrobenzylguanidine conjugated to iodine I 123 and used as a gamma-emitting imaging agent. The adrenergic tissue uptake and storage of I-123 metaiodobenzylguanidine (I-123 MIBG) mimics that of norepinephrine (NE). The distribution of this agent enables the scintigraphic imaging of neural crest tumors, such as neuroblastoma and pheochromocytoma.

Table 1. Record
IdentifierMLC-T-ONC-014543
FieldOncology and biomedicine
AbbreviationI-123 MIBG
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-014543",
  "term": "iodine-123 metaiodobenzylguanidine",
  "field": "Oncology and biomedicine",
  "definition": "The neurotransmitter analogue 3-nitrobenzylguanidine conjugated to iodine I 123 and used as a gamma-emitting imaging agent. The adrenergic tissue uptake and storage of I-123 metaiodobenzylguanidine (I-123 MIBG) mimics that of norepinephrine (NE). The distribution of this agent enables the scintigraphic imaging of neural crest tumors, such as neuroblastoma and pheochromocytoma.",
  "abbreviation": "I-123 MIBG",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iodine-123-metaiodobenzylguanidine/"
}

Record 9,529 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.