MLchartDataset catalogue

MK0731

Term · Oncology and biomedicine · MLC-T-ONC-015212

A synthetic small molecule with potential antineoplastic activity. MK0731 selectively inhibits kinesin spindle protein (KSP), which may result in the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and apoptosis in tumor cells that overexpress KSP.

Table 1. Record
IdentifierMLC-T-ONC-015212
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-015212",
  "term": "MK0731",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic small molecule with potential antineoplastic activity. MK0731 selectively inhibits kinesin spindle protein (KSP), which may result in the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and apoptosis in tumor cells that overexpress KSP.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/mk0731/"
}

Record 11,131 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.