MLchartDataset catalogue

MnSOD-plasmid liposomes

Term · Oncology and biomedicine · MLC-T-ONC-015218

A plasmid DNA encoding human manganese superoxide dismutase (MnSOD) and liposomally encapsulated with potential chemoprotective activity. When administered orally and localizing in the esophagus, MnSOD-plasmid liposomes express MnSOD, which scavenges reactive oxygen species (ROS); MnSOD scavenging of ROS may result in a reduction in ROS-mediated lipid peroxidation, apoptosis, and micro-ulceration in the epithelial lining of the esophagus.

Table 1. Record
IdentifierMLC-T-ONC-015218
FieldOncology and biomedicine
AbbreviationMnSOD-PL
Synonymsmanganese superoxide dismutase plasmid liposomes
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-015218",
  "term": "MnSOD-plasmid liposomes",
  "field": "Oncology and biomedicine",
  "definition": "A plasmid DNA encoding human manganese superoxide dismutase (MnSOD) and liposomally encapsulated with potential chemoprotective activity. When administered orally and localizing in the esophagus, MnSOD-plasmid liposomes express MnSOD, which scavenges reactive oxygen species (ROS); MnSOD scavenging of ROS may result in a reduction in ROS-mediated lipid peroxidation, apoptosis, and micro-ulceration in the epithelial lining of the esophagus.",
  "abbreviation": "MnSOD-PL",
  "synonyms": [
    "manganese superoxide dismutase plasmid liposomes"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/mnsod-plasmid-liposomes/"
}

Record 11,152 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.