MLchartDataset catalogue

Moxalactam

Term · Oncology and biomedicine · MLC-T-ONC-015294

A semisynthetic oxa-beta-lactam antibiotic, with antibacterial activity used mainly against gram-negative aerobic bacteria. Replacing the beta-lactam sulfur atom for an oxygen atom and the presence of the methyltetrazolethio moiety and the para-hydroxyphenylmalonyl group, increases the antibacterial activity of moxalactam. The 7-alpha-methoxy group and the para-hydroxyphenylmalonyl group increases the stability of this agent against beta-lactamases. The use of this agent has been associated with fatal bleeding events.

Table 1. Record
IdentifierMLC-T-ONC-015294
FieldOncology and biomedicine
Synonymslatamoxef
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-015294",
  "term": "Moxalactam",
  "field": "Oncology and biomedicine",
  "definition": "A semisynthetic oxa-beta-lactam antibiotic, with antibacterial activity used mainly against gram-negative aerobic bacteria. Replacing the beta-lactam sulfur atom for an oxygen atom and the presence of the methyltetrazolethio moiety and the para-hydroxyphenylmalonyl group, increases the antibacterial activity of moxalactam. The 7-alpha-methoxy group and the para-hydroxyphenylmalonyl group increases the stability of this agent against beta-lactamases. The use of this agent has been associated with fatal bleeding events.",
  "synonyms": [
    "latamoxef"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/moxalactam/"
}

Record 11,298 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.