multi-mode kinase inhibitor EOC317

{
  "id": "MLC-T-ONC-015356",
  "term": "multi-mode kinase inhibitor EOC317",
  "field": "Oncology and biomedicine",
  "definition": "An orally available, small molecule, multi-mode kinase inhibitor (MMKI), with potential antineoplastic activity. Upon oral administration, MMKI EOC317 targets, binds to and inhibits the activity of a variety of kinases, such as phosphatidylinositol 3 kinase (PI3K), and the receptor tyrosine kinases, fibroblast growth factor receptor (FGFR), angiopoietin-1 receptor (TIE 2), and vascular endothelial growth factor receptor-2 (VEGFR-2). This inhibition may result in an induction of apoptosis of susceptible tumors cells in which these kinases are overexpressed.",
  "synonyms": [
    "MMKI EOC317"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/multi-mode-kinase-inhibitor-eoc317/"
}