Multiepitope TARP-pulsed autologous dendritic cell vaccine

{
  "id": "MLC-T-ONC-015346",
  "term": "Multiepitope TARP-pulsed autologous dendritic cell vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A cell-based cancer vaccine comprised of autologous dendritic cells pulsed with multiple antigenic peptides derived from T-cell receptor gamma-chain alternate reading frame protein (TARP), with potential immunostimulatory and antineoplastic activities. Upon intradermal administration, multi-epitope (ME) TARP-pulsed autologous dendritic cell vaccine may stimulate anti-tumor cytotoxic T-lymphocyte (CTL) and antibody responses against TARP-expressing cancer cells, resulting in tumor cell lysis. The highly immunogenic nuclear protein TARP is expressed in a variety of cancer cell types.",
  "synonyms": [
    "multi-epitope TARP peptide-pulsed autologous dendritic cell vaccine",
    "multi-epitope TARP-pulsed autologous DC vaccine",
    "ME T-cell receptor gamma alternate reading frame protein peptide-pulsed autologous DC vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/multiepitope-tarp-pulsed-autologous-dendritic-cell-vaccine/"
}