NEDD8-activating enzyme inhibitor

{
  "id": "MLC-T-ONC-005712",
  "term": "NEDD8-activating enzyme inhibitor",
  "field": "Oncology and biomedicine",
  "definition": "A substance that blocks an enzyme called NEDD8-activating enzyme (NAE). NAE is involved in important cell functions, such as cell division. Blocking NAE may help keep cancer cells from growing and may kill them. Some NEDD8-activating enzyme inhibitors are being studied in the treatment of cancer. They are a type of targeted therapy. Also called NAE inhibitor.",
  "synonyms": [
    "NAE inhibitor"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/nedd8-activating-enzyme-inhibitor/"
}