MLchartDataset catalogue

NM-3

Term · Oncology and biomedicine · MLC-T-ONC-015529

An orally bioavailable antiangiogenic isocoumarin with potential antineoplastic activity. NM-3 inhibits vascular endothelial growth factor (VEGF), a pro-angiogenic growth factor, thereby inhibiting endothelial cell proliferation. This agent also induces apoptosis by a mechanism involving reactive oxygen species.

Table 1. Record
IdentifierMLC-T-ONC-015529
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-015529",
  "term": "NM-3",
  "field": "Oncology and biomedicine",
  "definition": "An orally bioavailable antiangiogenic isocoumarin with potential antineoplastic activity. NM-3 inhibits vascular endothelial growth factor (VEGF), a pro-angiogenic growth factor, thereby inhibiting endothelial cell proliferation. This agent also induces apoptosis by a mechanism involving reactive oxygen species.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/nm-3/"
}

Record 11,884 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.