nuclear factor-kappa B

{
  "id": "MLC-T-ONC-005957",
  "term": "nuclear factor-kappa B",
  "field": "Oncology and biomedicine",
  "definition": "A group of proteins that help control many functions in a cell, including cell growth and survival. These proteins also control the body’s immune and inflammatory responses. Nuclear factor-kappa B may be overactive or found in higher than normal amounts in some types of cancer cells. This may lead to cancer cell growth. High levels or overactivity of nuclear factor-kappa B may also lead to inflammatory disorders, such as asthma and ulcerative colitis, and autoimmune disorders, such as rheumatoid arthritis. Also called NF-kappa B and NF-kB.",
  "synonyms": [
    "NF-kappa B",
    "NF-kB"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/nuclear-factor-kappa-b/"
}