oncolytic Newcastle disease virus

{
  "id": "MLC-T-ONC-015652",
  "term": "oncolytic Newcastle disease virus",
  "field": "Oncology and biomedicine",
  "definition": "An oncolytic viral agent containing the oncolytic, live-attenuated strain of the paramyxovirus Newcastle disease virus (NDV), with potential antineoplastic activity. Upon administration, NDV specifically infects and replicates in cancer cells. This may result in a direct cytotoxic effect involving the lysis of tumor cells via apoptotic mechanisms and may eventually lead to an inhibition of cancer cell proliferation.",
  "abbreviation": "oncolytic NDV",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/oncolytic-newcastle-disease-virus/"
}