Oncolytic virus RT-01
Term · Oncology and biomedicine · MLC-T-ONC-015667
An oncolytic virus with potential antineoplastic and immunomodulating activities. Upon administration of RT-01, the oncolytic virus selectively targets and replicates in cancer cells without being able to infect and replicate in normal, healthy cells. This induces selective oncolytic virus-mediated cytotoxicity in cancer cells, which leads to cancer cell lysis. Following the lysis of infected cells, the replicated virus is released and can infect adjacent tumor cells, which both induces further tumor cell oncolysis and may activate the immune system to exert an anti-tumor immune response against the tumor cells.
| Identifier | MLC-T-ONC-015667 |
|---|---|
| Field | Oncology and biomedicine |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-015667",
"term": "Oncolytic virus RT-01",
"field": "Oncology and biomedicine",
"definition": "An oncolytic virus with potential antineoplastic and immunomodulating activities. Upon administration of RT-01, the oncolytic virus selectively targets and replicates in cancer cells without being able to infect and replicate in normal, healthy cells. This induces selective oncolytic virus-mediated cytotoxicity in cancer cells, which leads to cancer cell lysis. Following the lysis of infected cells, the replicated virus is released and can infect adjacent tumor cells, which both induces further tumor cell oncolysis and may activate the immune system to exert an anti-tumor immune response against the tumor cells.",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/oncolytic-virus-rt-01/"
}
Record 12,228 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.