Prednisone

{
  "id": "MLC-T-ONC-006885",
  "term": "Prednisone",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used to reduce inflammation and lower the body’s immune response. It is used with other drugs to treat leukemia, lymphoma, and mycosis fungoides (a type of skin lymphoma). It is also used alone or with other drugs to prevent or treat many other conditions. These include conditions related to cancer and its treatment, such as anemia (a low level of red blood cells) and allergic reactions. Prednisone is a type of therapeutic glucocorticoid.",
    "A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations."
  ],
  "abbreviation": "PRED",
  "synonyms": [
    "PRD",
    "Delta(1)-Cortisone",
    "deltacortisone",
    "deltadehydrocortisone",
    "metacortandracin",
    "Prednisonum",
    "delta 1-cortisone"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/prednisone/"
}