PSA RNA-pulsed dendritic cell vaccine

{
  "id": "MLC-T-ONC-016273",
  "term": "PSA RNA-pulsed dendritic cell vaccine",
  "field": "Oncology and biomedicine",
  "definition": "An autologous dendritic cell vaccine with potential immunostimulatory activity. Dendritic cells harvested from a prostate cancer patient are transfected with the mRNA encoding for prostate specific antigen (PSA), a tumor marker secreted by prostatic epithelial and ductal cells. When reintroduced back to the patient, these PSA RNA pulsed autologous dendritic cells may elicit a cytotoxic T-cell (CTL) response against PSA-positive prostate cancer cells.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/psa-rna-pulsed-dendritic-cell-vaccine/"
}