R-CHOP regimen

{
  "id": "MLC-T-ONC-007234",
  "term": "R-CHOP regimen",
  "field": "Oncology and biomedicine",
  "definitions": [
    "An abbreviation for a chemotherapy combination that is used to treat non-Hodgkin lymphoma and mantle cell lymphoma and is being studied in the treatment of other types of cancer. It includes the drugs rituximab, cyclophosphamide, doxorubicin hydrochloride (hydroxydaunorubicin), vincristine sulfate (Oncovin), and prednisone. Also called R-CHOP.",
    "A regimen consisting of cyclophosphamide, doxorubicin, prednisone, rituximab and vincristine that may be used for the treatment of AIDS-related B-cell lymphomas, Castleman disease, chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL), diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, gastric and nongastric MALT lymphomas, nodular lymphocyte-predominant Hodgkin lymphoma, mantle cell Lymphoma, nodal marginal zone lymphoma (NMZL), splenic marginal zone lymphoma (SMZL), Waldenström macroglobulinemia and lymphoplasmacytic lymphoma, and post-transplant lymphoproliferative disorders."
  ],
  "abbreviation": "CTX/DOX/MOAB IDEC-C2B8/PRED/VCR",
  "synonyms": [
    "R-CHOP",
    "CHOP-rituximab",
    "rituximab-cyclophosphamide-hydroxydaunorubicin-Oncovin-prednisone regimen",
    "cyclophosphamide/doxorubicin/prednisone/rituximab/vincristine",
    "Rituxan/CHOP",
    "rituximab/cyclophosphamide/doxorubicin/prednisone/vincristine"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/r-chop-regimen/"
}