radium Ra 224-labeled calcium carbonate microparticles

{
  "id": "MLC-T-ONC-016345",
  "term": "radium Ra 224-labeled calcium carbonate microparticles",
  "field": "Oncology and biomedicine",
  "definition": "A radiopharmaceutical composed of biodegradable calcium carbonate microspheres labeled with the alpha-emitting radioisotope radium Ra 224, with antineoplastic activity. Upon intraperitoneal (IP) administration of the radium Ra 224-labeled calcium carbonate microparticles, Ra 224 kills tumor cells through local emission of high energy alpha particles, causing DNA double-strand breaks. The short range effects of alpha emission allows for localized DNA damage with limited toxicity to nearby healthy tissue.",
  "synonyms": [
    "224Ra-labeled calcium carbonate micro-particles",
    "alpha-emitting 224Ra calcium carbonate microspheres",
    "Ra-224 alpha-emitting calcium carbonate microparticles"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/radium-ra-224-labeled-calcium-carbonate-microparticles/"
}