Recombinant macrophage colony-stimulating factor

{
  "id": "MLC-T-ONC-016445",
  "term": "Recombinant macrophage colony-stimulating factor",
  "field": "Oncology and biomedicine",
  "definition": "A recombinant therapeutic agent which is chemically identical to or similar to the endogenous protein cytokine macrophage colony-stimulating factor (M-CSF). Synthesized endogenously by mesenchymal cells, M-CSF stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series and can reverse treatment-related neutropenias. Recombinant M-CSF may also enhance antigen presentation and activate antitumoral cytotoxic T-cells.",
  "abbreviation": "rM-CSF",
  "synonyms": [
    "recombinant colony-stimulating factor 1",
    "colony stimulating factor 1"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/recombinant-macrophage-colony-stimulating-factor/"
}