relaxin mimetic AZD5462
Term · Oncology and biomedicine · MLC-T-ONC-016482
A mimetic of the endogenous heterodimeric insulin-like peptide relaxin, with potential vasodilating, cardioprotective and anti-fibrotic activities. Upon administration, relaxin mimetic AZD5462 mimics relaxin and may bind to relaxin receptor 1 (relaxin family peptide receptor 1; RXFP1). This may activate multiple relaxin-mediated signaling pathways and result in vasodilation, and anti-fibrotic and cardioprotective effects.
| Identifier | MLC-T-ONC-016482 |
|---|---|
| Field | Oncology and biomedicine |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-016482",
"term": "relaxin mimetic AZD5462",
"field": "Oncology and biomedicine",
"definition": "A mimetic of the endogenous heterodimeric insulin-like peptide relaxin, with potential vasodilating, cardioprotective and anti-fibrotic activities. Upon administration, relaxin mimetic AZD5462 mimics relaxin and may bind to relaxin receptor 1 (relaxin family peptide receptor 1; RXFP1). This may activate multiple relaxin-mediated signaling pathways and result in vasodilation, and anti-fibrotic and cardioprotective effects.",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/relaxin-mimetic-azd5462/"
}
Record 14,295 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.