Rifabutin

{
  "id": "MLC-T-ONC-007451",
  "term": "Rifabutin",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used to prevent the spread of a bacterium called in patients with advanced HIV (the virus that causes AIDS) infection. It blocks an enzyme that the bacteria need to grow. It is a type of antibiotic. Also called Mycobutin.",
    "A semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits bacterial DNA-dependent RNA polymerase, thereby suppressing the initiation of RNA formation and leading to inhibition of RNA synthesis and transcription."
  ],
  "synonyms": [
    "Mycobutin"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/rifabutin/"
}