Staphylococcus aureus protein A

{
  "id": "MLC-T-ONC-016862",
  "term": "Staphylococcus aureus protein A",
  "field": "Oncology and biomedicine",
  "definition": "A protein that resides in the microbial wall of staphylococcus aureus and interferes with opsonization by binding to the Fc portion of immunoglobulin. The protein has a deleterious effect on the epithelial cells that line the respiratory tract, and plays a role in the induction of pneumonia. Protein A also initiates polymorphonuclear cell migration into airway passages via TNFR1 activation.",
  "synonyms": [
    "S. aureus protein A",
    "Staph. Protein A"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/staphylococcus-aureus-protein-a/"
}