STI571

{
  "id": "MLC-T-ONC-008321",
  "term": "STI571",
  "field": "Oncology and biomedicine",
  "definition": "A drug used to treat certain types of leukemia and other blood cancers, gastrointestinal stromal tumors, skin tumors called dermatofibrosarcoma protuberans, and a certain type of a rare condition called systemic mastocytosis. It is also being studied in the treatment of other conditions and types of cancer. STI571 blocks certain proteins made by the BCR::ABL1, PDGFR, or c-KIT oncogene, which may help keep cancer cells from growing and may kill them. STI571 is a type of tyrosine kinase inhibitor. Also called Gleevec, imatinib mesylate, and Imkeldi.",
  "expansions": [
    "Gleevec",
    "imatinib mesylate",
    "Imkeldi"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/sti571/"
}