MLchartDataset catalogue

Sulfasalazine

Term · Oncology and biomedicine · MLC-T-ONC-016904

A synthetic salicylic acid derivative with affinity for connective tissues containing elastin and formulated as a prodrug, antiinflammatory sulfasalazine acts locally in the intestine through its active metabolites, sulfamide 5-aminosalicylic acid and salicylic acid, by a mechanism that is not clear. It appears inhibit cyclooxygenase and prostaglandin production and is used in the management of inflammatory bowel diseases.

Table 1. Record
IdentifierMLC-T-ONC-016904
FieldOncology and biomedicine
Synonymssalazosulfapyridine; sulphasalazine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-016904",
  "term": "Sulfasalazine",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic salicylic acid derivative with affinity for connective tissues containing elastin and formulated as a prodrug, antiinflammatory sulfasalazine acts locally in the intestine through its active metabolites, sulfamide 5-aminosalicylic acid and salicylic acid, by a mechanism that is not clear. It appears inhibit cyclooxygenase and prostaglandin production and is used in the management of inflammatory bowel diseases.",
  "synonyms": [
    "salazosulfapyridine",
    "sulphasalazine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/sulfasalazine/"
}

Record 15,768 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.