synthetic peptides E-PRA and E-PSM vaccine

{
  "id": "MLC-T-ONC-016950",
  "term": "synthetic peptides E-PRA and E-PSM vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A cancer vaccine consisting of E-PRA and E-PSM, two synthetic peptide analogs of PRAME (PReferential Antigen MElanoma) and PSMA (Prostate Specific Membrane Antigen), with potential immunostimulating activity. Upon direct administration into lymph nodes, synthetic peptides E-PRA and E-PSM vaccine may stimulate a cytotoxic T-lymphocyte (CTL) response against PRAME- and PSMA-expressing tumor cells. PRAME and PSMA are tumor-associated antigens upregulated and expressed on the cell surfaces of certain tumor cell types.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/synthetic-peptides-e-pra-and-e-psm-vaccine/"
}