Tecelra

{
  "id": "MLC-T-ONC-008564",
  "term": "Tecelra",
  "field": "Oncology and biomedicine",
  "definition": "A treatment used for adults with synovial sarcoma that has the MAGE-A4 antigen and has spread to other parts of the body or cannot be removed by surgery. It is used in patients who have certain HLA-A*02 antigens and have received chemotherapy. It is also being studied in the treatment of other types of cancer. Tecelra is made using a patient’s T cells (a type of immune system cell). A special T-cell receptor that can recognize the MAGE-A4 antigen is added to the T cells in the laboratory. These changed T cells are then grown in large numbers in the laboratory and given back to the patient by infusion. Tecelra binds to the MAGE-A4 antigen, which is found on some types of cancer cells. This helps the body’s immune system kill cancer cells. Tecelra is a type of cellular immunotherapy. Also called afamitresgene autoleucel.",
  "synonyms": [
    "afamitresgene autoleucel"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/tecelra/"
}