technetium Tc 99m epratuzumab
Term · Oncology and biomedicine · MLC-T-ONC-017015
A radioimmunoconjugate of the humanized IgG1 monoclonal antibody (MoAb) LL2 labeled with Technetium 99m (Tc-99m). Epratuzumab (MoAb LL2) recognizes CD22, a B-lymphocyte-restricted antigen expressed as a cytoplasmic protein in progenitor B cells, and as a cell surface protein in mature B cells. Tc-99m epratuzumab delivers gamma emission Tc-99m directly to B-lymphocyte lineage cells, thereby the agent may be used for diagnostic or treatment purposes.
| Identifier | MLC-T-ONC-017015 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | Tc 99m LL2 |
| Synonyms | Tc 99m monoclonal antibody LL2; technetium Tc 99m LL2 monoclonal antibody; technetium Tc 99m monoclonal antibody LL2 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-017015",
"term": "technetium Tc 99m epratuzumab",
"field": "Oncology and biomedicine",
"definition": "A radioimmunoconjugate of the humanized IgG1 monoclonal antibody (MoAb) LL2 labeled with Technetium 99m (Tc-99m). Epratuzumab (MoAb LL2) recognizes CD22, a B-lymphocyte-restricted antigen expressed as a cytoplasmic protein in progenitor B cells, and as a cell surface protein in mature B cells. Tc-99m epratuzumab delivers gamma emission Tc-99m directly to B-lymphocyte lineage cells, thereby the agent may be used for diagnostic or treatment purposes.",
"abbreviation": "Tc 99m LL2",
"synonyms": [
"Tc 99m monoclonal antibody LL2",
"technetium Tc 99m LL2 monoclonal antibody",
"technetium Tc 99m monoclonal antibody LL2"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/technetium-tc-99m-epratuzumab/"
}
Record 16,072 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.