Yttrium Y 90 epratuzumab

{
  "id": "MLC-T-ONC-017631",
  "term": "Yttrium Y 90 epratuzumab",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate consisting of the anti-CD22 monoclonal antibody epratuzumab chelated to the radioisotope yttrium-90 (Y 90). Yttrium Y 90 epratuzumab binds to tumor cells expressing CD22, delivering a cytotoxic dose of beta radiation. Epratuzumab is a humanized version of the murine monoclonal antibody LL2; CD22 is a B cell-restricted antigen present on the surfaces of mature B cells.",
  "synonyms": [
    "Y 90 Humanized Monoclonal Antibody LL2",
    "Yttrium Y 90 Humanized Monoclonal Antibody LL2"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/yttrium-y-90-epratuzumab/"
}