yttrium Y 90 anti-CD19 monoclonal antibody BU12

{
  "id": "MLC-T-ONC-017621",
  "term": "yttrium Y 90 anti-CD19 monoclonal antibody BU12",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate consisting of the murine IgG1 anti-CD19 monoclonal antibody (MoAb) BU12 labeled with the beta-emitting radioisotope yttrium Y 90 with radioisotopic and antibody activities. Yttrium Y 90 anti-CD19 monoclonal antibody BU12 binds to the CD19 molecule, specifically delivering cytotoxic beta radiation to CD19-expressing B cells. CD19 is a membrane antigen that is widely expressed during B-cell development, from pro-B-cell to early plasma cell stages.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/yttrium-y-90-anti-cd19-monoclonal-antibody-bu12/"
}