Yttrium Y 90 tacatuzumab tetraxetan
Term · Oncology and biomedicine · MLC-T-ONC-017639
A radioimmunoconjugate comprised of the monoclonal antibody HuAFP31, directed against alpha fetoprotein, that is conjugated to the chelating agent tetra-azacyclododecanetetra-acetic acid (DOTA) and radiolabeled with the beta-emitting radioisotope Yttrium Y90. Yttrium Y 90 tacatuzumab tetraxetan binds to tumor cells expressing alpha fetoprotein, selectively delivering a cytotoxic dose of beta radiation.
| Identifier | MLC-T-ONC-017639 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | Y90 DOTA MOAB HuAFP31 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-017639",
"term": "Yttrium Y 90 tacatuzumab tetraxetan",
"field": "Oncology and biomedicine",
"definition": "A radioimmunoconjugate comprised of the monoclonal antibody HuAFP31, directed against alpha fetoprotein, that is conjugated to the chelating agent tetra-azacyclododecanetetra-acetic acid (DOTA) and radiolabeled with the beta-emitting radioisotope Yttrium Y90. Yttrium Y 90 tacatuzumab tetraxetan binds to tumor cells expressing alpha fetoprotein, selectively delivering a cytotoxic dose of beta radiation.",
"abbreviation": "Y90 DOTA MOAB HuAFP31",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/yttrium-y-90-tacatuzumab-tetraxetan/"
}
Record 17,570 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.