MLchartDataset catalogue

Yttrium Y 90 tacatuzumab tetraxetan

Term · Oncology and biomedicine · MLC-T-ONC-017639

A radioimmunoconjugate comprised of the monoclonal antibody HuAFP31, directed against alpha fetoprotein, that is conjugated to the chelating agent tetra-azacyclododecanetetra-acetic acid (DOTA) and radiolabeled with the beta-emitting radioisotope Yttrium Y90. Yttrium Y 90 tacatuzumab tetraxetan binds to tumor cells expressing alpha fetoprotein, selectively delivering a cytotoxic dose of beta radiation.

Table 1. Record
IdentifierMLC-T-ONC-017639
FieldOncology and biomedicine
AbbreviationY90 DOTA MOAB HuAFP31
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-017639",
  "term": "Yttrium Y 90 tacatuzumab tetraxetan",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate comprised of the monoclonal antibody HuAFP31, directed against alpha fetoprotein, that is conjugated to the chelating agent tetra-azacyclododecanetetra-acetic acid (DOTA) and radiolabeled with the beta-emitting radioisotope Yttrium Y90. Yttrium Y 90 tacatuzumab tetraxetan binds to tumor cells expressing alpha fetoprotein, selectively delivering a cytotoxic dose of beta radiation.",
  "abbreviation": "Y90 DOTA MOAB HuAFP31",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/yttrium-y-90-tacatuzumab-tetraxetan/"
}

Record 17,570 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.