yttrium Y 90 anti-CD45 monoclonal antibody AHN-12

{
  "id": "MLC-T-ONC-017622",
  "term": "yttrium Y 90 anti-CD45 monoclonal antibody AHN-12",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate comprised of the monoclonal antibody AHN-12 conjugated to the radioisotope yttrium 90 with potential radioimmunotherapeutic activity. Yttrium Y 90 monoclonal antibody AHN-12 binds to the tyrosine phosphatase CD45, expressed on the surface of normal and malignant hematopoietic cells. After binding and internalization by CD45-expressing tumor cells, this agent may deliver a cytotoxic dose of beta radiation.",
  "abbreviation": "Y 90 AHN-12",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/yttrium-y-90-anti-cd45-monoclonal-antibody-ahn-12/"
}