Technetium Tc 99m glycopeptide
Term · Oncology and biomedicine · MLC-T-ONC-017018
A technetium Tc 99m radiopharmaceutical of a glutamate-rich peptide (GP) conjugated, via carbodiimide linker, to the heparin-like polysaccharide chitosan (CH) in a 1:1 ratio, with potential tumor targeting property. Upon administration, 99m Tc-glycopeptide targets and is taken up by glutamate-specific transporters on tumor cells. Upon internalization, the Tc99m moiety can be visualized upon scanning. GP may potentially be used as a drug carrier for antineoplastic drug delivery to tumor cells.
| Identifier | MLC-T-ONC-017018 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | 99mTc-GP |
| Synonyms | 99mTc-glycopeptide |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-017018",
"term": "Technetium Tc 99m glycopeptide",
"field": "Oncology and biomedicine",
"definition": "A technetium Tc 99m radiopharmaceutical of a glutamate-rich peptide (GP) conjugated, via carbodiimide linker, to the heparin-like polysaccharide chitosan (CH) in a 1:1 ratio, with potential tumor targeting property. Upon administration, 99m Tc-glycopeptide targets and is taken up by glutamate-specific transporters on tumor cells. Upon internalization, the Tc99m moiety can be visualized upon scanning. GP may potentially be used as a drug carrier for antineoplastic drug delivery to tumor cells.",
"abbreviation": "99mTc-GP",
"synonyms": [
"99mTc-glycopeptide"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/technetium-tc-99m-glycopeptide/"
}
Record 16,071 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.