temanogrel hydrochloride

{
  "id": "MLC-T-ONC-017059",
  "term": "temanogrel hydrochloride",
  "field": "Oncology and biomedicine",
  "definition": "The hydrochloride salt form of temanogrel, an orally bioavailable, selective inverse agonist of 5-hydroxytryptamine receptor 2A (5-HT2A), with potential anti-thrombotic and vasodilating activities. Upon oral administration, temanogrel targets, binds to and inhibits 5-HT2A expressed on platelet surfaces and in smooth muscle cells, thereby inhibiting 5-HT-mediated platelet aggregation and vasoconstriction. This may attenuate platelet aggregation and vasoconstriction, and improve blood flow.",
  "synonyms": [
    "Temanogrel"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/temanogrel-hydrochloride/"
}