WT1 peptide vaccine WT2725

{
  "id": "MLC-T-ONC-017580",
  "term": "WT1 peptide vaccine WT2725",
  "field": "Oncology and biomedicine",
  "definition": "A peptide cancer vaccine comprised of a peptide derived from Wilms tumor gene 1 (WT1) protein, with potential immunomodulating and antineoplastic activities. Upon administration, WT2725 may induce a specific cytotoxic T-lymphocyte (CTL) response against WT1-overexpressing tumor cells. WT1 protein, a zinc finger DNA-binding protein, is overexpressed in leukemic cells and in a vast number of non-hematological solid tumors.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/wt1-peptide-vaccine-wt2725/"
}